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TB-500
Size: 5mg
Cellular Peptide
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$65.00
1
In stock · Ships same day · Free shipping over $150
Compound Information
Technical specifications
Molecular Profile
What Is TB-500?
Synthetic version of Thymosin β4, a 43-amino-acid actin-regulating peptide.
Thymosin β4Tissue Repair
TypeSynthetic peptide
CAS Number77591-33-4
Molecular FormulaC212H350N56O78S
Molecular Weight4963.49 g/mol
Amino Acids43
Storage Requirements
Stability Information
Lyophilized powderReconstitute with bacteriostatic waterStore refrigerated
Lyophilized (powder)
-20°C · stable long-term
Reconstituted / in solution
2-8°C · use within 30 days
Product Information
TB-500 is a synthetic version of Thymosin Beta-4 (TB4), a naturally occurring 43-amino-acid peptide present in most human and animal tissues and one of the major actin-sequestering proteins in cells. It is widely studied as a research compound for its role in tissue repair and regeneration, where its primary mechanism involves the regulation of actin — a fundamental building block of the cellular cytoskeleton. By promoting actin polymerization, TB-500 has been investigated for its ability to upregulate cell migration, facilitating the movement of repair cells toward injury sites. Published research has also examined TB-500 for its role in promoting angiogenesis (new blood vessel formation), reducing inflammatory mediators at wound sites, and supporting the structural cellular mechanisms required for new tissue formation. Because it acts on broad cellular processes rather than tissue-specific pathways, TB-500 has been studied across diverse connective tissue types including tendons, ligaments, muscle, and cardiac tissue. This PEPCELL product is a research-grade compound manufactured for laboratory investigation and is not an FDA-approved drug.
Cell Migration
TB-500 (Thymosin Beta-4) is researched for upregulating actin polymerization, a process central to cytoskeletal reorganization and cell motility. By facilitating the migration of repair cells toward injury sites, TB-500 is studied for its potential to support the early structural phases of tissue regeneration.
Angiogenesis Support
Published research has examined TB-500's role in promoting angiogenesis — the formation of new blood vessels — which supplies oxygen and nutrients necessary for new tissue formation. This vascular support mechanism is studied as a complement to the inflammatory and growth factor pathways involved in repair.
Multi-Tissue Repair
Because TB-500 acts on fundamental cytoskeletal and vascular processes rather than tissue-specific pathways, it has been researched across a broad range of connective tissue types including tendons, ligaments, skeletal muscle, and cardiac tissue, where actin regulation and cell migration play key repair roles.
Handling & Storage
Published research protocols reference subcutaneous administration once or twice weekly. Store refrigerated at 2-8°C. Rotate injection sites.
Every batch is independently analyzed by a third-party laboratory for purity and identity before release. A batch-specific Certificate of Analysis (COA) is available for each lot.
Purity
99.3%
Lab
Janoshik Analytical Laboratory
Batch
TB500-2025-001
Test Date
2025-04-12
Orders placed before our daily cutoff ship the same business day. Free shipping on orders over $150, with tracking emailed as soon as your order leaves our facility.
Shipment protection covers your order against loss or damage in transit — if a protected order is lost or arrives damaged, our support team will arrange a replacement or resolution.
For in-vitro research and laboratory use only. This product is not a drug, supplement, food, or cosmetic, and has not been evaluated by the FDA.
Use is restricted to qualified researchers and laboratories operating within all applicable institutional, legal, and ethical guidelines. By purchasing, you confirm you are acquiring this product solely for lawful research purposes.
Frequently Asked Questions
TB-500 is a synthetic version of Thymosin Beta-4, a naturally occurring 43-amino-acid peptide found in most tissues and a major actin-sequestering protein. It is studied as a research compound for tissue repair, cell migration, and angiogenesis. This PEPCELL product is manufactured for laboratory investigation and is not an FDA-approved drug.
TB-500's primary researched mechanism is the regulation of actin, a key cytoskeletal protein. By promoting actin polymerization, it is studied for upregulating cell migration toward injury sites, while also being investigated for promoting angiogenesis and reducing inflammatory mediators — together supporting the structural processes of tissue regeneration.
TB-500 (Thymosin Beta-4) primarily acts through actin regulation, cell migration, and angiogenesis, providing structural and vascular support for new tissue formation. BPC-157 primarily modulates growth factors and inflammation through the nitric oxide and NF-kB pathways. They are frequently studied together because their mechanisms are complementary rather than overlapping — see the Wolverine (BPC-157 + TB-500) blend.
Reconstitute lyophilized TB-500 with bacteriostatic water by gently directing the stream down the inside wall of the vial. Swirl gently to dissolve — do not shake. Store the unreconstituted peptide at -20°C for long-term stability, or at 2-8°C for short-term use. After reconstitution, refrigerate at 2-8°C, protect from light, and use within 30 days.
No. This research-grade TB-500 is sold exclusively for in-vitro research, laboratory investigation, and educational purposes. It is not approved for human consumption, clinical use, or self-administration. Researchers should consult all applicable institutional guidelines and jurisdictional regulations before use.
