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The Gold Standard Growth Hormone Stack
The CJC-1295/Ipamorelin combination pairs a growth hormone-releasing hormone (GHRH) analog with a selective growth hormone secretagogue peptide (GHSP) to activate two complementary pathways of GH release simultaneously. CJC-1295 (Mod GRF 1-29) binds to GHRH receptors on somatotroph cells in the anterior pituitary, amplifying the amplitude of GH pulses, while Ipamorelin activates the ghrelin receptor (GHS-R1a) to increase the frequency of GH release without elevating cortisol or prolactin. Published research demonstrates that this dual-pathway activation produces synergistic GH output that significantly exceeds the sum of either peptide administered alone, a phenomenon documented in comparative secretagogue studies. The Ipamorelin component is notable for its high selectivity among GH secretagogues, with peer-reviewed literature confirming it triggers GH release with minimal effect on ACTH, cortisol, or prolactin levels even at elevated doses. This combination has become the most widely referenced growth hormone secretagogue stack in research literature, studied for its effects on body composition, lean mass accretion, fat metabolism, sleep architecture, and recovery from tissue injury. The pre-combined formulation ensures consistent molar ratios between the two peptides, eliminating variability that can occur when researchers prepare separate solutions.
Published research protocols reference subcutaneous administration 1-3 times daily. Store refrigerated at 2-8°C.
Published research protocols reference 100mcg each per injection, 2-3x daily in 12-16 week cycles. Consult applicable literature for specific research applications.
By simultaneously activating GHRH receptors (via CJC-1295) and ghrelin receptors (via Ipamorelin) on pituitary somatotroph cells, this combination produces a synergistic GH pulse that published research has documented as significantly greater than either peptide alone. The dual-pathway mechanism increases both the amplitude and frequency of GH secretion pulses, mimicking the body's natural multi-signal approach to growth hormone regulation.
Initial effects within first month
Research Studies
The Ipamorelin component provides exceptionally selective GH release without the cortisol and prolactin elevation commonly observed with other GH secretagogues such as GHRP-6 or GHRP-2. Published research in the European Journal of Endocrinology confirmed that Ipamorelin does not significantly affect ACTH, cortisol, or prolactin even at supraphysiological doses, making this combination uniquely suited for research requiring isolated GH axis stimulation.
Initial effects within first month
Research Studies
The pre-combined formulation delivers both peptides in a verified molar ratio within a single vial, eliminating the need to reconstitute, calculate, and draw from separate vials. This reduces preparation variability and potential contamination risks associated with handling multiple vials, which is particularly important for research protocols requiring consistent dosing across multiple administration time points.
Initial effects within first month
Store the CJC-1295/Ipamorelin combo lyophilized at -20°C for long-term storage. Once reconstituted with bacteriostatic water, store at 2-8°C (refrigerator) and use within 30 days. Both peptides in this combination have good reconstituted stability at refrigerator temperatures, but as with all peptide blends, minimize exposure to room temperature during handling to preserve the integrity of both active compounds.
Every batch of the CJC-1295/Ipamorelin combo is tested by Janoshik Analytical Laboratory using HPLC to verify the purity and ratio of both peptides in the blend, along with mass spectrometry to confirm the molecular identity of each component. Combo products require additional analytical validation to ensure both peptides are present at the correct molar ratio and that neither has degraded during the blending process. Our batches consistently achieve 99%+ purity for each component.
Reconstitute the CJC-1295/Ipamorelin combo with bacteriostatic water (BAC water) by slowly injecting the water along the vial wall. Allow both peptides to dissolve completely before use — this may take slightly longer than a single-peptide vial due to the combined lyophilized mass. Do not shake; gently swirl if needed. The reconstituted solution should appear clear and colorless.
This CJC-1295/Ipamorelin combination is sold for research purposes only and is not intended for human consumption. Both individual components have been the subject of published clinical studies — CJC-1295 in growth hormone release trials and Ipamorelin in selectivity and safety studies — but the combination product remains for investigational research use only. Consult with a qualified healthcare professional before designing any research protocol.
Important Notice
Not for human consumption. This product is sold exclusively for in-vitro research and laboratory use. It is not a drug, supplement, food item, or cosmetic and has not been evaluated by the FDA.
The research data and clinical references cited on this page are provided for educational reference only and do not constitute medical advice. This product must be handled by qualified research professionals in accordance with all applicable institutional and regulatory guidelines.
Use is restricted to qualified researchers or laboratories operating within appropriate legal and ethical research guidelines. By purchasing, you confirm you are acquiring this product solely for lawful research purposes.
Published research and educational content related to CJC-1295 NO DAC + IPA